BAsic information description Inflammation of the appendix. The appendix is a small, tubelike pouch that is part of the large intestine. The appendix has no known function, but it can become diseased. Symptoms vary widely. It can affect all ages and both sexes. frequent signs and symptoms Pain that begins close to the navel and moves toward the right-lower abdomen. Pain becomes persistent. It worsens with moving, breathing deeply, coughing, sneezing, walking, or being touched. Nausea...